To be safe, you want to consider the specific species of wood you use..... some are very prone to checking/cracking in small pieces. This is an area where it's best to be intimately knowledgeable with the wood species you choose..... some "move" more then others (even is a stabilized format), and others are more stable, with less "movement".
The glitch is that woods that are more stable/less likely to "move", are usually those that are harder/denser, and those, are more likely to check/split in smaller pieces.
Personally, if I were to make a knife with non-metallic bolsters, I would be inclined to do with it with synthetic material such as G10, Micarta, etc. The reason being, over the years I've learned NOT to build in anything that could be a potential failure point..... and wood bolsters for me, are just that.